4:2–4
First we have here call to prayer. It is a persistent prayer and characterized by thanksgiving. If in 3:16–17 - we have a liturgical - community prayer, here probably we reference to personal prayer.
Watching in prayer. In Paul’s understanding “watchfulness” always refers to waiting for the second coming of Christ.
See also 1 Thess 5:17–18; Phil 4:6.
Paul is also asking for an intercessory prayer for him. Even in prison, Paul was still thinking of new places of evangelization.
The Gospel is defined as “the mystery of Christ”. Yes, Christ indeed remains a mystery.
Paul needs God’s grace to properly reveal that mystery and for this he needs Colossians’ intercession.
4:5–6 - how do deal with those outside of the Church
Redeeming the time - kairos. to make wise and sacred use of every opportunity for doing good, so that zeal and well doing are as it were the purchase money by which we make the time our own.
The meaning is to use every opportunity to share the Gospel. How?
The way to share the Gospel - the speech in grace - graceful, pleasant, and seasoned with salt - that means giving taste. Sharing should be attractive to the listener.
Paul also places on us a responsibility - to be able to answer every person (1 Peter 3:15).
4:7–9
Two people are sent with the letter and they will pass on more information about Paul’s situation.
Tychicus (Acts 20:4–5; 2 Tim 4:12; Titus 3:12) and Onesimus (see the letter to Philemon). So a fugitive slave becomes Paul’s co-worker “faithful and beloved brother” - something to learn from Paul.
4:10–17 - Greetings from six people
4:15 - Greetings to the church in Laodicea and the house-church of Nymphas. Most of the churches at that time were house-churches gathered in the houses of certain families.
4:16 - Paul sent a letter also to Laodicea - some think it is the letter to the Ephesians. So, the letters of Paul were circulating among the communities.
4:17 - There is a special message to someone in Colossians called Archipus (Philemon 1:2). In Philemon he is called a fellow-soldier, but here he is reminded about the obligation of his ministry. Did he get slack in that ministry?
4:18 - (1 Cor 16:21; 2 Thess 3:17) - personal signature - a sign of authenticity. Again he reminds them to remember that he is in prison.
The final blessing is very short.